CacoReady
A cell-based and ready-to-use concept for in vitro intestinal absorption evaluation.
- A ready-to-use cell-based assay for rapid Caco-2 in-vitro assessment of drugs ability to cross the intestinal epithelium.
- The kits consist of 24 and 96 insert-integrated permeable support seeded with differentiated and polarized Caco-2 barriers on polycarbonate microporous filters.
CacoReady Applications
- A ready-to-use cell-based assay for rapid Caco-2 in-vitro assessment of drugs ability to cross the intestinal epithelium.
- Evaluation of oral absorption efficiency, oral bioavailability and oral toxicity
- Study of mechanisms involved in oral and intestinal absorption
- Suitable for research on new delivery systems
- Studies of Drug Transporters and Drug-Drug Interaction
CacoReady FDA Requirements
These four evaluation results pertaining to the compounds evaluated from data generated by the CacoReady kits are required by the FDA:
- Permeability Assay
- P-gp interactions
- BCRP interactions
- Toxicology Studies
CacoReady Kit Benefits
- CacoReady is extremely cost effective and does not require the management of site/in house cell production.
- Test kits may be available on demand according to your testing schedule.
- Using our proprietary shipping medium, the kits can be shipped at room temperature
- After incubation, kits are ready to assay with your compounds on day twenty-two
- User friendly and easy-handling system
- Kit is highly reproducible
- Adaptable to automation
- Discounted evaluations are available today
- Extensive testing experience demonstrates that results meet or surpass expectations.
Download CacoReady Technical Sheet
CacoReady Chart
| CacoReady Kit FORMATs | Product Numbers |
|---|---|
| CacoReady 24 Transwell (Costar) | KRECE-CCR01 |
| CacoReady 24 Transwell (Millipore) | KRECE-CCR03 |
| CacoReady 24 Well (individual transwell) | KRECE-CCR04 |
| CacoReady 96 Transwell (Costar) | KRECE-CCR50 |
| CacoReady 96 Transwell (Millipore) | KRECE-CCR52 |
| CacoReady 24 Well (without transwell) | KRECE-CCR02 |
| CacoReady 96 Well (without transwell) | KRECE-CCR51 |
