PreadyTake Mate1
A ready-to-use system for in vitro drug transporter evaluation.
- HEK293-MATE1 (SLC47A1 gene) is expressed mainly in the apical membrane kidney and liver; and it plays an important role in drug disposition and exception mediating the efflux of diverse substrates, particularly of organic cations.
- PreadyTake MATE1 is ready-to-use and consits of a tissue culture 96-plate seeded with transfected cells expressing MATE1 transporter as well as parental control cells.
Applications
- MATE1 substrate assessment for direct transport studies.
- MATE1 inhibitor assessment for drug-drug interaction studies.
- Models the net active transport event of barriers such as liver and kidney.
Benefits
- Available on demand
- Ready-to-use without in-house cell line development or acquisition and cell propagation
- Transportation and storage at room temperature in proprietary shipping medium
- User friendly and easy-handling system
- High reproducibility
- Adaptable to automation
Download PreadyTake MATE1 Technical Sheet
PreadyTake MATEO1 Chart
| PreadyTake MATE1 Kit FORMATs | Product Numbers |
|---|---|
| PreadyTake-MATE1 (96-Multiwell) | KRECE-MAT50 |
| PreadyTake-MATE1/CTRL 1:1 (96-Multiwell) | KRECE-MAT51 |
| PreadyTake-MATE1/CTRL Custom setup (96-Multiwell) | KRECE-MAT60 |
| PreadyTake-CTRL (96-Multiwell) | KRECE-HEK50 |
