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PreadyTake Mate1

A ready-to-use system for in vitro drug transporter evaluation.

Adaricell MATE-1 Kit For In Vitro Interaction of Drugs With Efflux Of Diverse Substrates, Particularly Of Organic Cations 

HEK293-MATE1 (SLC47A1 gene) is expressed mainly in the apical membrane kidney and liver; and it plays an important role in drug disposition and exception mediating the efflux of diverse substrates, particularly of organic cations.

PreadyTake MATE-1 is ready-to-use and consists of a tissue culture 96-plate seeded with transfected cells expressing MATE1 transporter as well as parental control cells.

PreadyTake MAKE-1 Applications

  • MATE1 substrate assessment for direct transport studies.
  • MATE1 inhibitor assessment for drug-drug interaction studies.
  • Models the net active transport event of barriers such as liver and kidney.

 

    PreadyTake FDA Requirements

    • The FDA requires the PreadyTake MATE-1 studies to be included in the final preclinical analysis.
    • PreadyTake MATE- is a product manufactured in compliance with ISO 9001:2015

     

    Cell Permeability Testing Market

     

    PreadyTake MAKE-1 Benefits

    • PreadyTake MATE-1  assays are cost effective and don’t not require the management of site/in house cell production
    • Testing kits are available on demand according to testing schedule
    • Shipped on day five of cell differentiation
    • Proprietary shipping medium allows for kits to be shipped and stored at room temperature
    • After incubation, kits are ready to assay with your compounds on days twelve through fifteen
    • The MATE-1 kit has demonstrated high reproducibility
    • Easily adaptable to automation
    • Extensive testing experience demonstrates that results meet or surpass expectations.
    • Discounted evaluations are available today

    Download PreadyTake MATE1 Technical Sheet

    PreadyTake MATEO1 Chart

    PreadyTake MATE1 Kit FORMATs Product Numbers
    PreadyTake-MATE1 (96-Multiwell) KRECE-MAT50
    PreadyTake-MATE1/CTRL 1:1 (96-Multiwell) KRECE-MAT51
    PreadyTake-MATE1/CTRL Custom setup (96-Multiwell) KRECE-MAT60
    PreadyTake-CTRL (96-Multiwell) KRECE-HEK50

    Get PreadyTake MATE1 96 Manual