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Cacoready

A cell-based and ready-to-use concept for in vitro intestinal absorption evaluation.
CacoReady
  • A ready-to-use cell-based assay for rapid Caco-2 in-vitro assessment of drugs ability to cross the intestinal epithelium.
  • The kits consist of 24 and 96 insert-integrated permeable support seeded with differentiated and polarized Caco-2 barriers on polycarbonate microporous filters.

CacoReady Applications

  • A ready-to-use cell-based assay for rapid Caco-2 in-vitro assessment of drugs ability to cross the intestinal epithelium.
  • Evaluation of oral absorption efficiency, oral bioavailability and oral toxicity
  • Study of mechanisms involved in oral and intestinal absorption
  • Suitable for research on new delivery systems
  • Studies of Drug Transporters and Drug-Drug Interaction

CacoReady FDA Requirements

These four evaluation results pertaining to the compounds evaluated from data generated by the CacoReady kits are required by the FDA:

  • Permeability Assay
  • P-gp interactions
  • BCRP interactions
  • Toxicology Studies

CacoReady Kit Benefits

  • CacoReady is extremely cost effective and does not require the management of site/in house cell production.
  • Test kits may be available on demand according to your testing schedule.
  • Using our proprietary shipping medium, the kits can be shipped at room temperature
  • After incubation, kits are ready to assay with your compounds on day twenty-two
  • User friendly and easy-handling system
  • Kit is highly reproducible
  • Adaptable to automation
  • Discounted evaluations are available today
  • Extensive testing experience demonstrates that results meet or surpass expectations.

CacoReady in the Literature

  • There are three papers that may also be of interest to you as they demonstrate the suitability of Caco-2 cells for testing permeability in three separate drug developments. More Info >>>

Cell Permeability Testing Market

Download CacoReady Technical Sheet Download

CacoReady Chart

CacoReady Kit FORMATs Product Numbers
CacoReady 24 Transwell (Costar) KRECE-CCR01
CacoReady 24 Transwell (Millipore) KRECE-CCR03
CacoReady 24 Well (individual transwell) KRECE-CCR04
CacoReady 96 Transwell (Costar) KRECE-CCR50
CacoReady 96 Transwell (Millipore) KRECE-CCR52
CacoReady 24 Well (without transwell) KRECE-CCR02
CacoReady 96 Well (without transwell) KRECE-CCR51