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PreadyPort MDR1

A ready-to-use tool for MDCKII-MDR1 monolayer assays.

PreadyPort MDR1
  • A ready-to-use monolayer cell-based assay for MDR1 in-vitro evaluation of drug interactions with the P-gp/MDR1 transporter. The assay is suitable for performing both inhibition and substrate assessments. The kit consists of 24- or 96-well permeable plates seeded with differentiated MDCKII cells expressing MDR1 as well as the parental cell line.

PreadyPort MDR1 Applications

  • MDR1 substrate assessment for direct transport studies
  • MDR1 inhibitor assessment for drug-drug interaction studies
  • Models the net transporter events of excretory cells and physiological barriers such as the human blood-brain barrier or the gastrointestinal tract and placenta

 

PreadyPort MDR1 FDA Requirements

  • The FDA requires the MDR1 studies to be included in the final preclinical analysis.
  • PreadyPort MDR1 is a product manufactured in compliance with ISO 9001:2015

 

PreadyPort MDR1 in the Literature

  • There are two papers that may also be of interest to you as they demonstrate the suitability of BCRP and MDR1 for testing permeability. More Info >>>

 

PreadyPort MDR1 Benefits

  • PreadyPort MDR1 assays are cost effective and don’t not require the management of site/in house cell production
  • Testing kits are available on demand according to testing schedule
  • After incubation, kits are ready to assay with your compounds on days twelve through fifteen
  • The MDR1 kit has demonstrated high reproducibility
  • Easily adaptable to automation
  • Extensive testing experience demonstrates that results meet or surpass expectations.
  • Discounted evaluations are available today
  • Shipped on day five of cell differentiation
  • Proprietary shipping medium allows for kits to be shipped and stored at room temperature

Cell Permeability Testing Market

 

Download PreadyPort MDR1 Technical Sheet

PreadyPort MDR1 Chart

PreadyPort-MDR1 Kit FORMATs Product Numbers
PreadyPort-MDR1 (24-Multiwell) KRECE-MDR01
PreadyPort-MDR1/CTRL 1:1 (24-Multiwell) KRECE-MDR02
PreadyPort-MDR1 (96-Multiwell) KRECE-MDR50
PreadyPort-MDR1/CTRL 1:1 (96-Multiwell) KRECE-MDR51
PreadyPort-MDR1/CTRL Custom setup (96-Multiwell) KRECE-MDR60
PreadyPort-CTRL (24-Multiwell) KRECE-CTR01
PreadyPort-CTRL (96-Multiwell) KRECE-CTR50

 

Get PreadyPort MDR1 (24 & 96) Manual

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