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PreadyPort MDR1

A ready-to-use tool for MDCKII-MDR1 monolayer assays.

PreadyPort MDR1
  • A ready-to-use monolayer cell-based assay for MDR1 in-vitro evaluation of drug interactions with the P-gp/MDR1 transporter. The assay is suitable for performing both inhibition and substrate assessments. The kit consists of 24- or 96-well permeable plates seeded with differentiated MDCKII cells expressing MDR1 as well as the parental cell line.

Applications

  • MDR1 substrate assessment for direct transport studies
  • MDR1 inhibitor assessment for drug-drug interaction studies
  • Models the net transporter events of excretory cells and physiological barriers such as the human blood-brain barrier or the gastrointestinal tract and placenta

Benefits

  • Available on demand
  • Ready-to-use without in-house cell line development or acquisition and cell propagation
  • Transportation and storage at room temperature in proprietary shipping medium
  • User friendly and easy-handling system
  • High reproducibility
  • Adaptable to automation

Download PreadyPort MDR1 Technical Sheet

PreadyPort MDR1 Chart

PreadyPort-MDR1 Kit FORMATs Product Numbers
PreadyPort-MDR1 (24-Multiwell) KRECE-MDR01
PreadyPort-MDR1/CTRL 1:1 (24-Multiwell) KRECE-MDR02
PreadyPort-MDR1 (96-Multiwell) KRECE-MDR50
PreadyPort-MDR1/CTRL 1:1 (96-Multiwell) KRECE-MDR51
PreadyPort-MDR1/CTRL Custom setup (96-Multiwell) KRECE-MDR60
PreadyPort-CTRL (24-Multiwell) KRECE-CTR01
PreadyPort-CTRL (96-Multiwell) KRECE-CTR50

 

Get PreadyPort MDR1 (24 & 96) Manual

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