PreadyPort MDR1
A ready-to-use tool for MDCKII-MDR1 monolayer assays.
- A ready-to-use monolayer cell-based assay for MDR1 in-vitro evaluation of drug interactions with the P-gp/MDR1 transporter. The assay is suitable for performing both inhibition and substrate assessments. The kit consists of 24- or 96-well permeable plates seeded with differentiated MDCKII cells expressing MDR1 as well as the parental cell line.
Applications
- MDR1 substrate assessment for direct transport studies
- MDR1 inhibitor assessment for drug-drug interaction studies
- Models the net transporter events of excretory cells and physiological barriers such as the human blood-brain barrier or the gastrointestinal tract and placenta
Benefits
- Available on demand
- Ready-to-use without in-house cell line development or acquisition and cell propagation
- Transportation and storage at room temperature in proprietary shipping medium
- User friendly and easy-handling system
- High reproducibility
- Adaptable to automation
Download PreadyPort MDR1 Technical Sheet
PreadyPort MDR1 Chart
| PreadyPort-MDR1 Kit FORMATs | Product Numbers |
|---|---|
| PreadyPort-MDR1 (24-Multiwell) | KRECE-MDR01 |
| PreadyPort-MDR1/CTRL 1:1 (24-Multiwell) | KRECE-MDR02 |
| PreadyPort-MDR1 (96-Multiwell) | KRECE-MDR50 |
| PreadyPort-MDR1/CTRL 1:1 (96-Multiwell) | KRECE-MDR51 |
| PreadyPort-MDR1/CTRL Custom setup (96-Multiwell) | KRECE-MDR60 |
| PreadyPort-CTRL (24-Multiwell) | KRECE-CTR01 |
| PreadyPort-CTRL (96-Multiwell) | KRECE-CTR50 |
